| ncRNA name | hsa-miR-15a-5p |
| ncRNA Category | miRNA |
| Disease name | age-related cataract |
| Species | Homo sapiens |
| Tissues/Cell_line | lens epithelial cells |
| Methods | qPCR |
| Expression pattern | up-regulated |
| Functional description | Expression of hsa-miR-15a-5p, hsa-miR-15a-3p, and hsa-miR-16-1-5p rose in lens epithelial cells in the three types of age-related cataract, which may suppress the expression of the anti-apoptotic genes bcl-2 and mcl-1, thereby contributing to the pathogenesis of age-related cataract through apoptosis. |
| PubMed ID | 25932180 |
| Year | 2015 |
| Title | Expression of the microRNAs hsa-miR-15a and hsa-miR-16-1 in lens epithelial cells of patients with age-related cataract. |
| Drug-related ncRNA | NO |
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